|
|
choloyl-CoA + glycine <=> H+ + glycocholate + CoA
|
2.3.1.65
bile acid-CoA:amino acid N-acyltransferase
|
–
|
BMK
|
|
BRENDA:
BR44066
KEGG:
R03718
MetaCyc:
GLYCINE-N-CHOLOYLTRANSFERASE-RXN
SABIO-RK:
3479
|
|
|
|
choloyl-CoA + H2O <=> H+ + cholic_acid + CoA
|
2.8.3.25
bile acid CoA-transferase
3.1.2.2
palmitoyl-CoA hydrolase
3.1.2.20
acyl-CoA hydrolase
3.1.2.27
choloyl-CoA hydrolase
|
–
–
–
–
|
K
|
|
BRENDA:
BR48553
KEGG:
R07296
MetaCyc:
3.1.2.27-RXN
SABIO-RK:
8638
|
|
|
|
choloyl-CoA + propionyl-CoA <=> CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA
|
2.3.1.16
acetyl-CoA C-acyltransferase
2.3.1.176
propanoyl-CoA C-acyltransferase
|
–
–
|
BMK
|
|
BRENDA:
BR48555
KEGG:
R03719
MetaCyc:
2.3.1.176-RXN
SABIO-RK:
3480
|
|
|
|
lithocholoyl-CoA + cholic_acid <=> choloyl-CoA + lithocholic_acid
|
2.8.3.25
bile acid CoA-transferase
|
–
|
|
|
BRENDA:
BR51766
KEGG:
R11539
MetaCyc:
RXN-17406
|
|
|
|
deoxycholoyl-CoA + cholic_acid <=> choloyl-CoA + deoxycholate
|
2.8.3.25
bile acid CoA-transferase
|
–
|
|
|
BRENDA:
BR51767
KEGG:
R07295
MetaCyc:
RXN-15366
|
|
|
|
choloyl-CoA + NAD+ <=> 7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+
|
1.3.1.115
3-oxocholoyl-CoA 4-desaturase
|
–
|
M
|
|
BRENDA:
BR52277
KEGG:
R12110
MetaCyc:
RXN-17400
|
|
|
|
ATP + cholic_acid + CoA <=> AMP + diphosphate + choloyl-CoA
|
6.2.1.7
cholate---CoA ligase
|
–
|
MK
|
|
BRENDA:
BR90
KEGG:
R02794
MetaCyc:
CHOLATE--COA-LIGASE-RXN
|
|
|
|
choloyl-CoA + NAD+ <=> 3-dehydrocholoyl-CoA + NADH + H+
|
1.1.1.213
3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.395
3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase
|
–
–
|
M
|
|
BRENDA:
BS230635-a
MetaCyc:
BAIAEUBSP-RXN
|
|
|
|
choloyl-CoA + taurine <=> H+ + taurocholate + CoA
|
2.3.1.65
bile acid-CoA:amino acid N-acyltransferase
|
–
|
BMK
|
|
BRENDA:
BS321166
KEGG:
R03720
MetaCyc:
RXN-9800
SABIO-RK:
3481
|
|
|
|
chenodeoxycholoyl-CoA + NAD+ <=> choloyl-CoA + NADH + H+
|
1.1.1.395
3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase
|
–
|
M
|
|
MetaCyc:
RXN-17399
|
|
|
|
7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oyl-CoA + cholic_acid <=> 7alpha,12alpha-dihydroxy-3-oxochol-4-enoate + choloyl-CoA
|
2.8.3.25
bile acid CoA-transferase
|
–
|
M
|
|
MetaCyc:
RXN-21335
|
|
|
|
7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + cholic_acid <=> 7alpha-hydroxy-3-oxochol-4-enoate + choloyl-CoA
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-21338
|
|
|
|
7beta-hydroxy-3-oxochol-4-en-24-oyl-CoA + cholic_acid <=> choloyl-CoA + 7beta-hydroxy-3-oxochol-4-enate
|
2.8.3.25
bile acid CoA-transferase
|
–
|
M
|
|
MetaCyc:
RXN-21344
|
|
|
|
dATP + cholic_acid + CoA <=> dAMP + diphosphate + choloyl-CoA
|
6.2.1.7
cholate---CoA ligase
|
–
|
|
|
BRENDA:
BS344
|
|
|
|
choloyl-CoA + D-alanine <=> CoA + D-alpha-alanylcholate
|
2.3.1.65
bile acid-CoA:amino acid N-acyltransferase
|
–
|
|
|
BRENDA:
BS321169
|
|
|
|
choloyl-CoA + alpha-fluoro-beta-alanine <=> CoA + 2-fluoro-beta-alanylcholate
|
2.3.1.65
bile acid-CoA:amino acid N-acyltransferase
|
–
|
|
|
BRENDA:
BS321168
|
|
|
|
choloyl-CoA + beta-Alanine <=> CoA + beta-alanylcholate
|
2.3.1.65
bile acid-CoA:amino acid N-acyltransferase
|
–
|
|
|
BRENDA:
BS321167
|
|
|
|
choloyl-CoA + NADP+ <=> 3-oxocholoyl-CoA + NADPH + H+
|
1.1.1.213
3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
|
–
|
|
|
BRENDA:
BS230635
|
|
|
|
allodeoxycholoyl-CoA + cholic_acid <=> allodeoxycholate + choloyl-CoA
|
2.8.3.25
bile acid CoA-transferase
|
–
|
|
|
BRENDA:
BS437005
|
|